Your opinion: Celebrex vs. Mobic

By boston T Latest Activity February 1, 2010 at 5:19 pm Views 83,557 Replies 25

boston T

I've been taking 200 mg of Celebrex daily for my arthritis. I have a friend at work who recently started taking Mobic. She said it was safer (or at least that's what she was told).

I don't know anything about Mobic. Does anyone have an opinion?

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  • J-Walk
    J-Walk January 25, 2017 at 8:07 pm   
    Edited January 25, 2017 at 8:19 pm by J-Walk

    This thread is a bit dated, but I figure people might happen onto it from time to time. I'm a hippie (Rt hip replacement 11mns ago) and have been bone on bone about 2 years and have no ball left on my femurs. I'm getting surgery on my other hip (L) in 2 weeks. I have spent a total of 5 days on Tramadol (1st surgery with no NSAIDs) and only taken Diladid 3 times (with NSAIDS) during my 2nd emergency surgery. My 1st one went badly and resulted in emergency surgery (infection then massive UEDVT blood clot in Jugular) and delayed my 2nd hip surgery for almost a year. I wouldn't have made it thru without the NSAIDs. I was on Mobic 15mg during the before/thru 2nd surgery at which time I switched to Celebrex 200mg because of my warfarin treatment.

    Basically, I would say that Celebrex 200mg (once per day) isn't as strong as the Mobic 15mg for me, although it's hard to say for sure. My hip is really degenerating right now, so it really hard to compare how Mobic worked 6mns ago vs Celebrex now. I will say that I accidently ran out of my Celebrex recently and could no longer walk, thus realizing I had run out a week earlier. Celebrex is really helping me alot so it's hard to judge. I feel more comfortable drinking a couple of beers while on Celebrex than Mobic as there are strong warnings against that on Mobic. I would also say that I have noticed everybody's body chemistry is different depending on the person. Asprin, Tylonal amd Naprosyn are no more effective than tic tacs foe me. One may work well for you and another may not, so try both. Also you must give them a couple weeks to a month to work up to their full power and reduce your inflammation/pain. If you come off after that much time and don't notice a difference, then it wasn't working.

    So my take on pain killers vs anti-inflammatories… pain killers use narcotics to cover up the problem. Anti-inflammatories reduce the swellng that causes most arthritic pain thus removing the root of the problem instead of covering it up. When you have a lot of inflammation, it takes a while for the NSAIDS to get the swelling and the pain down. When you come off of them, the swelling comes back (at least for me) and I can no longer walk. Plus, NSAIDS are not addictive (major side effect!) When I talk to other people limping or on the cane and they say they are in painkillers, I ask about their NSAIDS and most are not on any. I tell them to get a new doc, get on the NSAIDs and their quality of life will go way up. Sadly, I don't know anybody who had listened to that advise.

    I hope my experiences help some of you in the future!

  • wineracquet
    wineracquet March 24, 2016 at 2:13 pm   

    I was prescribed Celebrex for shoulder impingement problems by 2 orthopedic doctors and also after shoulder surgery. My co-pay was $20 a month. My GP doc told me to try Mobic (Meloxicam) instead. The co-pay is $1.96 and it works at least as well as Celebrex did for me. I have had no noticeable side effects with either one. It appears to me that, for profit purposes, since Celebrex has no generic counterpart, big pharma encourages Dr's to prescribe it over cheaper alternatives.

  • death2fake
    death2fake December 31, 2013 at 10:37 pm   

    im 32 years old. i have RA and osteoarthritis. ive had several surgeries, loaded with mass amounts of narc pain meds you name it. got sick of it all. my entire left leg is garbage. i went back for my last ankle surgery a couple years ago to file some stuff down and remove some floaters. 6 weeks after that is when i desided to go off of allthe pills. spent a year recovering my body from the garbage i put into it, spent alot of time doing light work outs, and all seemed well. after about a year of no meds pain started returning. fired all my drs and went on the search for someone that wouldnt cram narcs down my throat and found meloxicam, it worked ok for normal flare ups, but nothing on the real bad days, found a sports med dr who was helping me with a slipped disk and he suggested celebrex. it seemed to work great. i just went 5 days without it cause of insurence mix ups and i was reminded very much so how much i love celebrex. i work hard for a living and workout as well, no heart problems. i also need a ankle transplant just to give a idea of how much it helps. i was at 80% cartalege loss 2 years ago. i feel grinding but not much pain. with that said my back,shoulder and elbows feel better also im guessing i prolly have srthritis in all them areas as well.

  • rah2435
    rah2435 July 6, 2012 at 1:15 pm   

    I have pretty severe OA in both knees - i'm 55 and have always exercised and been in good physical shape. My rheumatologist gave me celebrex, I took it once and it made me feel dizzy - I felt like my blood pressure went up. So this was replaced with mobic. I haven't tried the mobic yet for fear it will have the same effect BUT I need to do something. Guess I should at least give it a try. I FEAR replacements! Also been looking at stem cell injections…who knows?

  • gkp
    gkp July 25, 2012 at 9:41 am   

    I would really encourage you to have the knee replacement surgery. I had it 3 years ago when I was 50 and could kick myself for not doing it sooner. I am like a new person. The operation went very well, the recovery time was not long and the physical therapy was very helpful. The pain during recovery was short lived and they did give me pain meds. Please don't fear replacements!!!

  • DEM88
    DEM88 November 7, 2016 at 7:09 am   

    Hello! I just wanted to tell you this…do not fear the replacement. I just had my right knee done on Oct 14th. While the first few days were not so much fun…every day since has gotten better and better. I can honestly say i have alot less pain now than i did before surgery. My left needs to be replaced as well…Almost looking forward to it๐Ÿ˜‰

  • rah2435
    rah2435 July 25, 2012 at 9:55 am   

    thanks so much for your reply!
    I've heard this from several people - I do know ONE person who has had problems with their replacement, but most say they love it.
    Can I ask a few questions:
    Did you have both knees done or just one?
    Can you move around just like you did before, i.e., are there any restrictions in your movement?
    How about the fact that they supposedly wear out in 15 years or so? Does this concern you?

    I guess it's just the thought of having my leg opened up, bones sawed and slabs of metal and plastic glue to me that makes me freak. :-) However, the pain is getting pretty bad and I can't even walk very far now. Soooo…I guess it might just be time…

    thanks again!

  • crwtobias
    crwtobias September 28, 2010 at 10:33 am   

    I've had RA for 2 years now and have used both Mobic & Celebrex along with Methotextrate once a week. Mobic caused side effects including stomach probs and quite frankly really didn't do much so I switched to Celebrex; I get more relief from Celebrex and have had no side effects although there are a lot of warnings out there about it.

  • Jackdean
    Jackdean September 28, 2010 at 6:59 am   

    Mobic is also used for arthritis, inflammation and pain. It is available in 7.5 and 15mg dosages. You can find more info at

  • TPB1960
    TPB1960 February 19, 2010 at 4:42 pm   

    I have been on Mobic for years because it is supposed to be safer than Celebrex and I have other health issues that put me at risk using Celebrex. Mobic has worked very well for me. I need Hip Replacement surgery and have extreme pain. Without the Mobic I can not walk.

  • BettySC
    BettySC September 23, 2010 at 8:40 am   

    I have found that BC powders help me more than any of the medicines mentioned here. They are just powdered aspirin with a little caffeine. Because they are powdered, the get into your system quickly, and I think that is why they work better. They taste bad, but they work! Goody powders have some Tylenol mixed in, which is useless because it doesn't work on infllammation. Aspirin can irritate the stomach, as all NSAIDs can.

  • KitToTheKat777
    KitToTheKat777 February 21, 2010 at 11:55 am   

    Celebrex unfortunately does nothing for me yet Mobic seems to give me some relief. The best was Voixx which they took off the market but it was great!

  • mingarue
    mingarue February 21, 2010 at 11:13 pm   

    What do you suggest for me? I haven't tried regular arthritic medications because my Dr. has me on a pain pill with Naproxen. I have arthritis in both knees. I 've often thought it probably isn't good for one to stay on pain killers right?

  • flymire
    flymire February 25, 2010 at 7:48 pm   

    Vioxx was the best thing I ever took for my knees. I was so upset when they took it off the market. I think they should have left you and your Dr. decide if the benefit outweighed the risk. They switched me to Celebrex which did NOTHING! Naproxen did ok but I was having alot of gastro issues(stomach). I now take Mobic which isn't impressing me(I just started it). The major thing that sucks is that I'm only 41 and "too young" for replacement although I have bone on bone. I'm going through my 5th or 6th orthovisc series. They work less with each subsequent series.

  • smalltwngrl7
    smalltwngrl7 September 28, 2010 at 10:44 am   

    I know what you mean about the Vioxx! I don't know where you are, but I had my hip replaced at 43 & know people that were younger~maybe you should try another Dr. unless it is your insurance co.

  • I Drop Everything
    I Drop Everything September 23, 2010 at 11:04 pm   

    I've been on Celebrex, and Tramodol for 2 years. Before that I was taking Motrin 800mg. for many years which I couldn't live without. I have Spondolithis since 1979, and worked 31 years with it. I am retired now and have more problems, OA on my right knee and Arthritist on my right hip(bone on bone). I need a hip replacement but the doctor wants me to lose weight before he does it. He wanted to treat my knee with Orthovisc but my insurance doesn't cover it. So, I got a shot of cortisone. After 4 days it started to help me it's not a cure but some improvement. I now am in the process of losing weight and exercising. I swim and walk in a pool three times a week and go into the jacuzzi after. If I am in a lot of pain I take a Percocet, with the other drugs. I have lived in pain for so many years I some times break down and cry, which helps. Than I pick myself up again and ask G_D for help and go on. Ps. I also have degenerative disc disease. If anyone can give me words of encouragement I would love to hear it. I weighted 320 last year and believe this has cause most of my problems. I now am 267 but I have a long way to go. The doctor asked me if I considered band surgery, etc. I told him I thought about it but decided to do it naturally. I am a compulsive overeater, and belonged to Overeatters Anonymous and lost over 100 lbs in 1975, then had an accident at work in 1979, where I hurt my back and have gained all the weight back plus. I am basically using the OA program to regain my sanity and it works if you work it.
    Thanks for listening…

  • Lee Cara
    Lee Cara April 2, 2016 at 9:52 pm   

    I understand your difficult situation. I have all lumbar bone on bone, OA from neck down, sacrals needs surgery, bone on bone knees and agony pain with hip flare-ups. I have MS, fibromyalgia, diabetes 2, HBP, IBS, migraines, carpel tunnel, allergies galore, etc. had to stop working in 1997. Right now have to decide to go on tramadol and neurontin. I am 56 and scared of new regimen with potential side effects. Did not want to have back stimulator implanted. Have had injections all over. Have been using Celebrex or ibuprofen, tylenol3, nortriptyline, carisoprodol, Valium and prednisone. Pain flares can be excruciating and all the meds don't help enough. I'm overweight but would never do the surgery. If u lost so much weight, hang in there. You can do it.

  • Sleepless Peeps
    Sleepless Peeps February 1, 2010 at 6:24 pm   

    I've never heard of Mobic. Are you sure that's spelled right?

    I like Celebrex. Works for me.

  • Cactus Pete
    Cactus Pete February 3, 2010 at 1:08 pm   

    Yeah, that's the spelling. Here's a link

    I'm hoping someone has tried it and can let me know what they think.

  • rmorlo
    rmorlo February 19, 2010 at 4:13 pm   

    I have used both. I honestly can't tell the difference between one or the other.

  • Gregor
    Gregor February 19, 2010 at 10:00 pm   

    I've used Mobic. For me it was as effective as M&Ms, but the M&Ms taste better.

    If my pain is relatively minor Celebrex gives me some relief. If the pain is severe, as it usually is, Celebrex isn't any better than Mobic or plain old aspirin.

  • Tam48
    Tam48 February 21, 2010 at 7:07 am   

    I have been on celebrex for 12-years now. I was once put on Mobic . I started to have chest pains.. So, back on the celebrex I went .I have to agree that the Celebrex is not any better than the mobic, or any of the other INSAIDs they are offering.I now have been moved up on my dosage from the 200mg a day to 400mg a day..of the celebrex. The doctors have added a lot more meds that I have to take for my conditons..Good luck on your choice.

  • mingarue
    mingarue February 21, 2010 at 11:15 pm   

    Is Celebrex an over the counter or perscription?

  • Lana
    Lana February 22, 2010 at 10:09 am   

    Welcome Mingarue to Arthritis Connect.

    Yes, Celebrex is a medication that must be prescribed by your doctor. It is FDA approved to treat osteoarthritis, rheumatoid arthritis, and acute pain. It is an NSAID (nonsteroidal anti-inflammatory: an anti-inflammatory drug that does not contain steroids.) It is not a narcotic.

    Again welcome, and thank you for joining us here.

  • Crescent Bay
    Crescent Bay April 14, 2010 at 11:50 am   

    I have been on Celebrex, 200 mg once a day, for the past three years. My family doctor has warned me to stop taking it because of the risk for heart attack and stroke. Walgreens had also begun stapling a separate letter to my prescription, with the same warnings. Celebrex was really designed for short-term use. It worked very well for me and reduced my pain about 85% and I was very sad to have to give it up.

    I am now on Ultracet, which reduces my pain about 40%. I am 62 years old and work full-time and plan to continue working to 67. I have OA in the mid joint of both feet, in both knees, and in the joint at the base of the thumb just above the wrist in both hands. I am also beginning to feel it in one of my shoulders. I am trying to learn to live with a higher degree of pain and not allow it to impact my daily activities. But it really sucks.

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